????? ??? ??? ?????? ?????????? ??? ?? ????? ?? ????? ???? :????? ??? ??? ?????? ?????????? ??? ?? ????? ?? ????? ??????? ????? ???????? ???? ???? ???? ?????? ?????? ??????? ???????? ???? ????? ??? ???? ?? ??????? ????? ?????? ??????. ???? ?? ???? ????? ???? ????? ??????? ???????? ???? ??????? ??????.The FDA’s final rule marks a substantial regul